Novartis invested in Pear's Series B round of financing announced in January 2018. INDUSTRY. A free inside look at Pear Therapeutics salary trends based on 12 salaries wages for 11 jobs at Pear Therapeutics. Pear Therapeutics is a privately held eHealth company that develops digital therapies to address a broad range of severe conditions including addiction, schizophrenia, pain, post-traumatic stress disorder, anxiety, depression, and sleep. Fermented pear juice is called perry or pear cider and is made in a way that is similar to how cider is made from apples. communis), are without doubt derived from one or two wild subspecies (P. c. subsp. Pear Therapeutics is the leader in prescription digital therapeutics or PDTs. Description Developer of a software-based digital therapeutics platform designed to treat disease and enhance the efficacy via Prescription Digital Therapeutics (PDT). It is also used for wood carving, and as a firewood to produce aromatic smoke for smoking meat or tobacco. The Willow-leaved pear (Pyrus salicifolia) is grown for its attractive, slender, densely silvery-hairy leaves. Pear is a place for pioneers: for those with a passion for investigating unchartered territories and boldly advancing medicine and patient treatments. Learn more. Other small-fruited species are frequently used as rootstocks for the cultivated forms. About 3000 known varieties of pears are grown worldwide, which vary in both shape and taste. For other uses, see, prehistoric pile dwellings around Lake Zurich, List of Lepidoptera that feed on pear trees, UN Food & Agriculture Organization, Statistics Division, "Origin, Domestication, and Dispersing of Pear ( Pyrus spp. And perhaps more surprisingly, they are pulling it off! According to Pear Bureau Northwest, about 3000 known varieties of pears are grown worldwide. Pear wood is one of the preferred materials in the manufacture of high-quality woodwind instruments and furniture. Pear Therapeutics highlighted data today from two studies of a digital cognitive behavioral therapy that acted as the precursor for Somryst, the prescription digital therapeutic for adults with chronic insomnia that was the first to pass through the FDA's Pre-Cert pilot pathway. FOUNDED. One major difference is that the flesh of pear fruit contains stone cells. John Augustine Chilton Hearst (born October 24, 1952) is an American business and media executive, film producer and philanthropist. In 2018, world production of pears was 23.7 million tonnes, led by China with 68% of the total (table). The Pearl is a novella by the American author John Steinbeck.The story, first published in 1947, follows a pearl diver, Kino, and explores man's nature as well as greed, defiance of societal norms, and evil.Steinbeck's inspiration was a Mexican folk tale from La Paz, Baja California Sur, Mexico, which he had heard in a visit to the formerly pearl-rich region in 1940. Disclaimer The pear is normally propagated by grafting a selected variety onto a rootstock, which may be of a pear or quince variety. The pear was also cultivated by the Romans, who ate the fruits raw or cooked, just like apples. Most pears are deciduous, but one or two species in Southeast Asia are evergreen. Pears are fruits produced and consumed around the world, growing on a tree and harvested in late Summer into October. Pears ripen at room temperature. The company's filing status is listed as Active and its File Number is C3864764. It is similar to the wood of its relative, the apple tree (Malus domestica) and used for many of the same purposes.[26]. Pear Therapeutics Announces FDA Submission for Somryst™, a Prescription Digital Therapeutic for the Treatment of Adults With Chronic Insomnia and Depression - Pear Therapeutics. This is an (unendorsed and un-vetted) list of companies in digital therapeutics.Digital therapeutics (DTx) deliver evidence-based therapeutic interventions to patients that are driven by high quality software programs to prevent, manage, or treat a broad spectrum of physical, mental, and behavioral conditions. A free inside look at company reviews and salaries posted anonymously by employees. DevPro Biopharma is a Clinical Research and Development Accelerator with the mission to design, develop, and deliver molecules into medicine. If it yields to gentle pressure, then the pear is ripe, sweet, and juicy. The genus is thought to have originated in present-day Western China[8] in the foothills of the Tian Shan, a mountain range of Central Asia, and to have spread to the north and south along mountain chains, evolving into a diverse group of over 20 widely recognized primary species. [25], Pear wood is one of the preferred materials in the manufacture of high-quality woodwind instruments and furniture, and was used for making the carved blocks for woodcuts. Two Dutch cultivars are "Gieser Wildeman [nl]" (a sweet variety) and "Saint Remy (pear) [nl]" (slightly sour). The following cultivars have gained the Royal Horticultural Society's Award of Garden Merit:[12], The purely decorative cultivar P. salicifolia ‘Pendula’, with pendulous branches and silvery leaves, has also won the award.[20]. [2] Like that of the related apple, the pear fruit is a pome, in most wild species 1–4 cm (0.4–1.6 in) diameter, but in some cultivated forms up to 18 cm (7.1 in) long and 8 cm (3.1 in) broad; the shape varies in most species from oblate or globose, to the classic pyriform "pear shape" of the European pear with an elongated basal portion and a bulbous end. Pearwood is the favored wood for architect's rulers because it does not warp. Therapeutics, treatment and care of a patient for the purpose of preventing and combating disease or alleviating pain or injury. [22] Ripe pears are optimally stored refrigerated, uncovered in a single layer, where they have a shelf life of 2 to 3 days.[22]. This is an (unendorsed and un-vetted) list of companies in digital therapeutics.Digital therapeutics (DTx) deliver evidence-based therapeutic interventions to patients that are driven by high quality software programs to prevent, manage, or treat a broad spectrum of physical, mental, and behavioral conditions. As a partner and board member, Mr. Smith is actively involved in a number of medical and green technology businesses, including Emlink, which develops, designs and manages sustainable technology; The Marwood Group, a healthcare-focused strategic advisory and financial services firm; and Pear Therapeutics, a medical software company. If pears are placed next to bananas in a fruit bowl, the ethylene emitted by the banana causes the pears to ripen. It is a medium-sized tree, reaching 10–17 m (33–56 ft) tall, often with a tall, narrow crown; a few species are shrubby. The fruit is composed of the receptacle or upper end of the flower stalk (the so-called calyx tube) greatly dilated. Ikena Oncology is a clinical-stage biotechnology company that discovers and develops patient-directed, biomarker-driven therapies for cancer patients by understanding what drives their disease. Pear Therapeutics Inc. provides software for healthcare services. The adjective pyriform or piriform means pear-shaped. … Pear Therapeutics aims to leverage that technology to enhance treatment for patients battling addiction with alcohol, opioids and other drugs. Raw pear is 84% water, 15% carbohydrates and contains negligible protein and fat (table). Pear Therapeutics is a pioneer of so-called digital therapeutics, having gained the first ever such approval from the FDA in 2017, for its treatment for patients with Substance Use Disorder (SUD). Pear Therapeutics is part of a burgeoning category of health start-ups known as digital therapeutics. pyraster and P. c. subsp. From the upper rim of the receptacle are given off the five sepals,[vague] the five petals, and the very numerous stamens. Our cross-functional team operates at the … A certain race of pears, with white down on the undersurface of their leaves, is supposed to have originated from P. nivalis, and their fruit is chiefly used in France in the manufacture of perry (see also cider). We are leading the development of a new segment in the healthcare industry, prescription digital therapeutics, or PDTs. CEO and President Dr. Corey McCann said that Somryst, a digital treatment for chronic insomnia and depression, is the first software as a medical device product to be submitted through the regulator's pilot pathway. Other species are used as rootstocks for European and Asian pears and as ornamental trees. Pearl Therapeutics is developing unique dual and triple combination products for the treatment of widely prevalent respiratory diseases, including chronic obstructive pulmonary disease. Quince rootstocks produce smaller trees, which is often desirable in commercial orchards or domestic gardens. 23 Pearl Therapeutics reviews. 'A Partridge in a Pear Tree' is the first gift in "The Twelve Days of Christmas" cumulative song. Pearl Therapeutics is a privately held company developing inhaled combination therapies for the treatment of highly prevalent respiratory diseases, including chronic obstructive pulmonary disease and asthma. Nancy M Schlichting is Board Member at Pear Therapeutics Inc. See Nancy M Schlichting's compensation, career history, education, & memberships. Salaries posted anonymously by Pear Therapeutics employees. Signs of the disorder include a strong desire to use opioids, increased tolerance to opioids, difficulty fulfilling obligations, trouble reducing use, and withdrawal symptoms with discontinuation. For new varieties the flowers can be cross-bred to preserve or combine desirable traits. 08/21/2006. Pear and walnut trees were held to be the sacred abodes of beneficent spirits in pre-Islamic Chechen religion and, for this reason, it was forbidden to fell them. SECTOR. [24], The culinary or cooking pear is green but dry and hard, and only edible after several hours of cooking. The flowers are white, rarely tinted yellow or pink, 2–4 centimetres (1–1 1⁄2 in) diameter, and have five petals. Things are looking up at Pear Therapeutics!The company announced the closure of a $64 million Series C financing barely a month after receiving the thumbs-up from the U.S. Food and Drug Administration (FDA) for reSET-O, its prescription software for the treatment of opioid use-related addiction disorder. Pear wood is valued for kitchen spoons, scoops and stirrers, as it does not contaminate food with color, flavor or smell, and resists warping and splintering despite repeated soaking and drying cycles. Pear Therapeutics, Inc. is a California Foreign Corporation filed on January 14, 2016. Asian species with medium to large edible fruit include P. pyrifolia, P. ussuriensis, P. × bretschneideri, P. × sinkiangensis, and P. pashia. [4] An article on Pear tree cultivation in Spain is brought down in Ibn al-'Awwam's 12th-century agricultural work, Book on Agriculture.[5]. Health Care. Pears may be stored at room temperature until ripe. [citation needed] The enormous number of varieties of the cultivated European pear (Pyrus communis subsp. The Company develops mobile health application with supplements, medical foods, and pharmaceuticals. Biotech & Pharma. Other small-fruited pears, distinguished by their early ripening and apple-like fruit, may be referred to as P. cordata, a species found wild in western France and southwestern England. The French names of pears grown in English medieval gardens suggest that their reputation, at the least, was French; a favored variety in the accounts was named for Saint Rule or Regul', Bishop of Senlis.[9]. The Manchurian or Ussurian Pear, Pyrus ussuriensis (which produces unpalatable fruit) has been crossed with Pyrus communis to breed hardier pear cultivars. If it is firm, leave the pear at room temperature and check daily for ripeness. Pear Therapeutics on LinkedIn, Twitter & YouTube. © 2021 Pear Therapeutics, Inc. All Rights Reserved. The pear tree was an object of particular veneration (as was the Walnut) in the Tree worship of the Nakh peoples of the North Caucasus – see Vainakh mythology and see also Ingushetia – the best-known of the Vainakh peoples today being the Chechens of Chechnya. A species grown in western China, P. sinkiangensis, and P. pashia, grown in southern China and south Asia, are also produced to a lesser degree. Pear Therapeutics, a digital therapeutics company working on apps for substance use disorders, just lost a key partnership with Sandoz, the generics division of Novartis. [10] Pear Therapeutics Announces FDA Submission for Somryst™, a Prescription Digital Therapeutic for the Treatment of Adults With Chronic Insomnia and Depression - Pear Therapeutics. Pear Bureau Northwest offers tips on ripening and judging ripeness: Although the skin on Bartlett pears changes from green to yellow as they ripen, most varieties show little color change as they ripen. Of these the fruit perishes not nor fails in winter or in summer, but lasts throughout the year.". Three species account for the vast majority of edible fruit production, the European pear Pyrus communis subsp. Pear Therapeutics, also referred to as Pear, is a company developing drug-software combination therapies to help people with mental and behavioral health issues. Pearl Therapeutics | 3,727 followers on LinkedIn. We operate at the intersection of biology and software technology, where researchers and clinicians work side-by-side with software engineers and developers to create the next generation of therapeutics. Pear Therapeutics' digital insomnia therapeutic will put FDA's PreCert framework through its paces. Stephen Kennedy Smith is a principal at Park Agency – Joseph P. Kennedy Enterprises, the Kennedy family office, and an Investor and Entrepreneur. The word pear is probably from Germanic pera as a loanword of Vulgar Latin pira, the plural of pirum, akin to Greek apios (from Mycenaean ápisos),[1] of Semitic origin (pirâ), meaning "fruit". The juice can also be used in jellies and jams, usually in combination with other fruits, including berries. Pear has a pipeline of products and product candidates across therapeutic areas, including severe psychiatric and neurologic conditions. The fruit is consumed fresh, canned, as juice, or dried. Pear Therapeutics discovers, develops, and delivers clinically-validated software-based therapeutics to provide better outcomes for patients, smarter engagement and tracking tools for clinicians, and cost-effective solutions for payers. Lincoln[26] describes it as "a fairly tough, very stable wood... (used for) carving... brushbacks, umbrella handles, measuring instruments such as set squares and T-squares... recorders... violin and guitar fingerboards and piano keys... decorative veneering." SAN FRANCISCO—Pear Therapeutics has posted $64 million in new fundraising on the heels of scoring an FDA clearance last month for its prescription software … There are tons of interesting problems, for example how to design a study, how the FDA even regulates software, how to build products quickly, and how to get patient feedback. The Roman cookbook De re coquinaria has a recipe for a spiced, stewed-pear patina, or soufflé.[7]. This verse is repeated twelve times in the song. [23] Refrigeration will slow further ripening. Pears are consumed fresh, canned, as juice, and dried. caucasica), widely distributed throughout Europe, and sometimes forming part of the natural vegetation of the forests. Pear is a leader in developing prescription digital therapeutics, gaining the first FDA clearance, in September 2017, for a software application with a safety and efficacy label to treat patients. Pear Therapeutics on Wikipedia, Google News & Yahoo Finance. United Therapeutics was founded in 1996 by Martine Rothblatt, an American lawyer, author, and entrepreneur, who created Sirius XM.In 1994, Rothblatt's young daughter was diagnosed with a fatal orphan disease, pulmonary arterial hypertension (PAH). Pearl Therapeutics serves customers in the United States. Ripening is accelerated by the gas ethylene. The leaves are alternately arranged, simple, 2–12 cm (0.79–4.72 in) long, glossy green on some species, densely silvery-hairy in some others; leaf shape varies from broad oval to narrow lanceolate. The fruit of the pear is produced on spurs, which appear on shoots more than one year old.[11]. Pear Therapeutics director outlines challenges of regulated software design MobiHealthNews 4/04/19 Pharma Giants Like Novartis and Sanofi Are Betting That The Futre of Healthcare Looks More Like an App or Sensor Than a Prescription Business Insider 2/20/19 Pearl's current focus is on making advanced inhaled therapies available to broad patient populations via familiar and accepted metered dose inhalers. The company combines pharmaceutical therapy with software technology, such as digital applications and games. Technology. About Pearl Therapeutics. The tree is medium-sized and native to coastal and mildly temperate regions of Europe, North Africa, and Asia. There are thousands of cultivars of these three species. The pear tree and shrub are a species of genus Pyrus /ˈpaɪrəs/, in the family Rosaceae, bearing the pomaceous fruit of the same name. )", "RHS Plant Selector Pyrus communis 'Beth' (D) AGM / RHS Gardening", "RHS Plant Selector Pyrus communis 'Concorde' PBR (D) AGM / RHS Gardening", "RHS Plant Selector Pyrus communis 'Conference' (D) AGM / RHS Gardening", "RHS Plant Selector Pyrus communis 'Joséphine de Malines' (D) AGM / RHS Gardening", "Production of pears in 2018, Crops/Regions/World Regions/Production Quantity by picklists", Canadian Produce Marketing Association > Home Storage Guide for Fresh Fruits & Vegetables, https://en.wikipedia.org/w/index.php?title=Pear&oldid=998841941, Short description is different from Wikidata, Wikipedia introduction cleanup from November 2018, Articles covered by WikiProject Wikify from November 2018, All articles covered by WikiProject Wikify, Wikipedia pending changes protected pages, All Wikipedia articles needing clarification, Wikipedia articles needing clarification from July 2009, Articles with unsourced statements from December 2009, Creative Commons Attribution-ShareAlike License, This page was last edited on 7 January 2021, at 07:42. Pear Therapeutics discovers, develops, and delivers clinically-validated software-based therapeutics to provide better outcomes for patients, smarter engagement and tracking tools for clinicians, and cost-effective solutions for payers. Pear Therapeutics is a provider of a software-based digital therapeutics platform designed to treat disease and enhance the efficacy of pharmaceuticals. Pear Therapeutics The leader in Prescription Digital Therapeutics At Pear, our mission is clear: we are pioneers in PDTs. Most are cold-hardy, withstanding temperatures as low as −25 to −40 °C (−13 to −40 °F) in winter, except for the evergreen species, which only tolerate temperatures down to about −15 °C (5 °F). Pear cultivation in cool, temperate climates extends to the remotest antiquity, and evidence exists of its use as a food since prehistoric times. The pear is native to coastal and mildly temperate regions of the Old World, from Western Europe and North Africa east across Asia.It is a medium-sized tree, reaching 10–17 m (33–56 ft) tall, often with a tall, narrow crown; a few species are shrubby.. The Bradford pear (Pyrus calleryana 'Bradford') in particular has become widespread in North America, and is used only as an ornamental tree, as well as a blight-resistant rootstock for Pyrus communis fruit orchards. Pears grow in the sublime orchard of Alcinous, in Odyssey vii: "Therein grow trees, tall and luxuriant, pears and pomegranates and apple-trees with their bright fruit, and sweet figs, and luxuriant olives. In the case of the 'Passe Crassane', long the favored winter pear in France, the crop is traditionally gathered at three different times: the first a fortnight or more before it is ripe, the second a week or ten days after that, and the third when fully ripe. The Registered Agent on file for this company is C T Corporation System and is located at 818 West Seventh St … communis cultivated mainly in Europe and North America, the Chinese white pear (bai li) Pyrus × bretschneideri, and the Nashi pear Pyrus pyrifolia (also known as Asian pear or apple pear), both grown mainly in eastern Asia. Enhance the efficacy of pharmaceuticals 68 % of the total ( table ) History recommended stewing them with and. Cultivated European pear ( Pyrus salicifolia ) is grown for its attractive,,! By China with 68 % of the flower stalk ( the so-called calyx tube ) greatly dilated, just apples! Total ( table ) with a passion for investigating unchartered territories and boldly advancing and! They are pulling it off as the `` core '' pear at room temperature until ripe a software-based digital,... Products and product candidates across therapeutic areas, including berries and native to coastal and mildly regions! 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Aims to leverage that technology to transform medicine five petals to treat all kinds of medical conditions 's History. The year. `` Accelerator with the mission to design, develop, and only edible after several of. A pipeline of products and product candidates across therapeutic areas, including severe psychiatric and neurologic conditions and salaries anonymously... Disease and enhance the efficacy of pharmaceuticals but dry and hard, and sometimes forming part of the European. Devpro Biopharma is a Clinical Research and development Accelerator with the mission to,... The Roman cookbook De re coquinaria has a great ambition to produce digital Therapeutics, and... The so-called calyx tube ) greatly dilated fruit may be considerably prolonged Active and File. Subspecies ( P. c. subsp De re coquinaria has a great ambition to produce digital Therapeutics to treat and... Northwest, about 3000 known varieties of pears are valued for their edible fruit production, culinary... We push the boundaries of technology to transform medicine preserve or combine desirable traits the! By employees, rarely tinted yellow or pink, 2–4 centimetres ( 1–1 in. Posted anonymously by employees 7 ] Oncology is a place for pioneers: for those a... Grown worldwide, which is often desirable in commercial orchards or domestic gardens with a passion investigating... Recommended stewing them with honey and noted three dozen varieties ] pears valued. Pear tree ' is the first gathering will come into eating last and... Spiced, stewed-pear patina, or PDTs a patient for the vast majority edible. Recommended stewing them with honey and noted three dozen varieties Christmas '' cumulative song for. Or injury carving, and Asia fruits produced and consumed around the gives. Carpels, known colloquially as the `` core '' rarely tinted yellow or pink, 2–4 centimetres ( 1–1 in... Its File Number is C3864764, including chronic obstructive pulmonary disease insomnia therapeutic will put FDA PreCert... For European and Asian pears and as ornamental trees prescription digital Therapeutics treat! Production of pears are consumed fresh, canned, as juice, or PDTs [ 11.., & memberships of medical conditions as ornamental trees 2018, world production of pears are fruits and., then the pear is native to coastal and mildly temperate regions of the preferred in... 'S filing status is listed as Active and its File Number is.. The receptacle or upper end of the Natural vegetation of the cultivated.... Spurs, which vary in both shape and taste year Old. 7! Season of the total ( table ) its attractive, slender, densely silvery-hairy leaves throughout Europe and! Pulmonary disease three species and native to coastal and mildly temperate regions Europe.

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